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Article

Hepatocyte TEAD1 drives epithelial-stromal remodeling during cholestatic liver injury

2026-05-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> Primary sclerosing cholangitis (PSC) is a progressive cholangiopathy characterized by ductular remodeling, inflammation, and periportal fibrosis, for which effective medical therapies remain limited. The Hippo pathway effector TEAD1 has been implicated in liver regeneration and fibrogenesis; however, its role in cholestatic injury remains poorly defined. We investigat...

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Literature Corpus work
c2f41498-ae40-55b9-a585-341adf0ae9b0
DOI
10.64898/2026.05.21.726939
Open publication

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Hepatocyte TEAD1 drives epithelial-stromal remodeling during cholestatic liver injuryDOI 10.64898/2026.05.21.726939
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