Article

Conserved long noncoding RNA <i>TILAM</i> promotes liver fibrosis through interaction with PML in hepatic stellate cells

2023-07-30

Abstract excerpt

<h4>Background & Aims</h4> Fibrosis is the common endpoint for all forms of chronic liver injury, and progression of fibrosis leads to the development of end-stage liver disease. Activation of hepatic stellate cells (HSCs) and their transdifferentiation to myofibroblasts results in the accumulation of extracellular matrix (ECM) proteins that form the fibrotic scar. Long noncoding (lnc) RNAs regulate the activity...

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Literature Corpus work: 60125867-83a9-5709-ab93-fa0f61e155e1
DOI: 10.1101/2023.07.29.551032

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