Article
Polycystic liver diseases: congenital disorders of cholangiocyte signaling.
Gastroenterology - 1 Jun 2011
Strazzabosco Mario, Somlo Stefan
Abstract excerpt
Polycystic liver diseases (PLD) are inherited disorders of the biliary epithelium, caused by genetic defects in proteins associated with intracellular organelles, mainly the endoplasmic reticulum and the cilium. PLD are characterized by the formation and progressive enlargement of multiple cysts scattered throughout the liver parenchyma, and include different entities, classified based on their pathology,...
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