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Article

Role of YAP1 Signaling in Biliary Development, Repair, and Disease

24 Jan 2022

Abstract excerpt

Yes-associated protein 1 (YAP1) is a transcriptional coactivator that activates transcriptional enhanced associate domain transcription factors upon inactivation of the Hippo signaling pathway, to regulate biological processes like proliferation, survival, and differentiation. YAP1 is most prominently expressed in biliary epithelial cells (BECs) in normal adult livers and during development. In the current...

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PMID: 35073587
DOI: 10.1055/s-0041-1742277

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