Article

A Pandas complex adapted for piRNA-guided transposon silencing

2019-04-13

Abstract excerpt

The repression of transposons by the Piwi-interacting RNA (piRNA) pathway is essential to protect animal germ cells. In Drosophila ovaries, Panoramix (Panx) enforces transcriptional silencing by binding to the target-engaged Piwi-piRNA complex, although the precise mechanisms by which this occurs remain elusive. Here, we show that Panx functions together with a germline specific paralogue of a nuclear export fact...

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Literature Corpus work: 9ff3176f-acb0-5088-9ef8-6674187bed1e
DOI: 10.1101/608273

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