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Article

The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline.

The EMBO journal - 16 Nov 2011

Pane Attilio, Jiang Peng, Zhao Dorothy Yanling, Singh Mona, Schüpbach Trudi

Abstract excerpt

In a broad range of organisms, Piwi-interacting RNAs (piRNAs) have emerged as core components of a surveillance system that protects the genome by silencing transposable and repetitive elements. A vast proportion of piRNAs is produced from discrete genomic loci, termed piRNA clusters, which are generally embedded in heterochromatic regions. The molecular mechanisms and the factors that govern their expression are...

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Identifiers

PMID: 21952049
DOI: 10.1038/emboj.2011.334
PMCID: PMC3243597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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