Article

A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage

2018-11-19

Abstract excerpt

The piRNA pathway protects germline genomes through transcript cleavage of selfish genetic elements, such as transposons, in the cytoplasm and their transcriptional silencing in the nucleus. Here, we describe a mechanism by which the nuclear and cytoplasmic arms of the silencing mechanism are linked. During mitosis of Drosophila spermatogonia, nuclear Piwi interacts with nuage, the compartment that mediates the c...

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Literature Corpus work: 87f1b937-bb86-5c1a-b05b-d99f8a2c4a03
DOI: 10.1101/474049

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A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuageDOI 10.1101/474049Read

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