Article

Epigenetic and Transcriptional Dysregulation in CD4+ T cells of Patients with Atopic Dermatitis

2021-12-03

Abstract excerpt

<h4>ABSTRACT</h4> Atopic dermatitis (AD) is one of the most common skin disorders in children. Disease etiology involves genetic and environmental factors, with the 29 independent AD risk loci enriched for risk allele-dependent gene expression in the skin and CD4+ T cell compartments. We investigated epigenetic mechanisms that may account for genetic susceptibility in CD4+ T cells. To understand gene regulatory a...

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Literature Corpus work: c2d3b81e-72e3-5e7c-8803-bf2dc69f7746
DOI: 10.1101/2021.12.03.471059

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