Article

Integrative Data Analysis to Uncover Transcription Factors Involved in Gene Dysregulation of Nine Autoimmune and Inflammatory Diseases

2024-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Autoimmune and inflammatory diseases are a group of > 80 complex diseases caused by loss of immune tolerance for self-antigens. The biological mechanisms of autoimmune diseases are largely unknown, preventing the development of effective treatment options. Integrative analysis of genome-wide association studies and chromatin accessibility data has shown that the risk variants of autoimmune disea...

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Literature Corpus work: 8599a609-087f-54dc-98cc-a9059333284e
DOI: 10.1101/2024.04.24.591013

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