Article

Prediction and evolution of the molecular fitness of SARS-CoV-2 variants: Introducing SpikePro

2021-04-12

Abstract excerpt

The understanding of the molecular mechanisms driving the fitness of the SARS-CoV-2 virus and its mutational evolution is still a critical issue. We built a simplified computational model, called SpikePro, to predict the SARS-CoV-2 fitness from the amino acid sequence and structure of the spike protein. It contains three contributions: the viral transmissibility predicted from the stability of the spike protein, t...

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Literature Corpus work: c2b2c588-9205-5f7b-aacd-6dfb07f42a62
DOI: 10.1101/2021.04.11.439322

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