Article

Investigating the role of binding free energy, binding affinity and antibody escape in the evolution of SARS-CoV-2 spike protein

2022-10-17

Abstract excerpt

SARS-CoV-2 is considered a pandemic virus and presents a major strain on public health globally. SARS-CoV-2 infects mammalian cells by binding to its receptor, ACE2 which is mediated by the viral spike glycoprotein, specifically the receptor binding domain (RBD) within the spike protein. Recent development of vaccines against SARS-CoV-2 spike protein are currently the best strategy to reduce morbidity and mortalit...

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Literature Corpus work: bf1c1762-9fdf-5d73-9e54-412c35db2fb2
DOI: 10.1101/2022.10.15.512351

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