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Article

T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblasts

2024-07-31

Abstract excerpt

<h4>ABSTRACT</h4> T cells and structural cells coordinate appropriate inflammatory responses and restoration of barrier integrity following insult. Dysfunctional T cells precipitate skin pathology occurring alongside altered structural cell frequencies and transcriptional states, but to what extent different T cells promote disease-associated changes remains unclear. We show that functionally diverse circulating...

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Literature Corpus work
bc6fcb3d-6b3f-51a9-9864-14aed034ff55
DOI
10.1101/2024.07.31.606077
Open publication

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T cells promote distinct transcriptional programs of cutaneous inflammatory disease in keratinocytes and dermal fibroblastsDOI 10.1101/2024.07.31.606077
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