Article
A unified framework integrating parent-of-origin effects for association study.
PloS one - 1 Jan 2013
Xiao Feifei, Ma Jianzhong, Amos Christopher I
Abstract excerpt
Genetic imprinting is the most well-known cause for parent-of-origin effect (POE) whereby a gene is differentially expressed depending on the parental origin of the same alleles. Genetic imprinting is related to several human disorders, including diabetes, breast cancer, alcoholism, and obesity. This phenomenon has been shown to be important for normal embryonic development in mammals. Traditional association...
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