Article

Identification of PCNA interacting protein motifs in human DNA polymerase delta

2020-03-03

Abstract excerpt

DNA polymerase delta (Polδ) is a highly processive essential replicative DNA polymerase. In humans, Polδ holoenzyme consists of p125, p50, p68, and p12 subunits and recently, we have shown that p12 exists as a dimer. Extensive biochemical studies suggest that all the subunits of Polδ interact with the processivity factor proliferating cell nuclear antigen (PCNA) to carry out a pivotal role in genomic DNA replicati...

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Literature Corpus work: c287cfc1-9df0-521d-8a22-e0e14928b56d
DOI: 10.1101/2020.02.29.971473

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