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Article

Functional roles of p12, the fourth subunit of human DNA polymerase delta.

The Journal of biological chemistry - 26 May 2006

Li Hao, Xie Bin, Zhou Yajing, Rahmeh Amal, Trusa Sandra, Zhang Sufang, Gao Yan, Lee Ernest Y C, Lee Marietta Y W T

Abstract excerpt

Mammalian DNA polymerase delta (pol delta), a key enzyme of chromosomal DNA replication, consists of four subunits as follows: the catalytic subunit; p125, which is tightly associated with the p50 subunit; p68, a proliferating cell nuclear antigen (PCNA)-binding protein; and a fourth subunit, p12. In this study, the functional roles of the p12 subunit of pol delta were studied. The inter-subunit interactions of...

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Identifiers

PMID: 16510448
DOI: 10.1074/jbc.M600322200

Genes

PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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