Article

Structure of the Thin Filament in Human iPSC-derived Cardiomyocytes and its Response to Heart Disease

2023-10-26

Abstract excerpt

Cardiovascular diseases are a leading cause of death worldwide, but our understanding of the underlying mechanisms is limited, in part because of the complexity of the cellular machinery that controls the heart muscle contraction cycle. Cryogenic electron tomography (cryo-ET) provides a way to visualize diverse cellular machinery while preserving contextual information like subcellular localization and transient c...

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Literature Corpus work: c27f55e2-171e-50f8-917b-fd24d8ebb5ff
DOI: 10.1101/2023.10.26.564098

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