Article

Low-dose cytokine immunotherapy of solid cancers enabled by phagocytic-competent protein co-crystals

2023-04-07

Abstract excerpt

Protein therapeutics are often compromised by sub-optimal biodistribution contributing to poor efficacy and adverse events. Drug delivery mechanisms better able to target protein drugs to the disease site and provide localized, sustained release have the potential to transform therapeutic standards. PODS ® crystals (PODS) are natural-mimetic, micron-scale protein co-crystals engineered to incorporate a protein ca...

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Literature Corpus work: c270fab1-8138-5bd1-8c68-ff44e15be181
DOI: 10.1101/2023.04.06.534711

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