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Beyond Exosomes: Ultrapurified Phospholipoproteic Complex (PLPC) as a Scalable Immunomodulatory Platform to Reprogram Immune Suppression in Metastatic Cancer

2025-04-07

Abstract excerpt

Dendritic exosomes (DEX) have demonstrated immunostimulatory potential in can-cer immunotherapy, but their clinical translation remains limited due to cryodepend-ence, heterogeneity, and poor scalability. To overcome these challenges, we developed a phospholipoprotein complex (PLPC), derived from dendritic cell secretomes and sta-bilized via ultracentrifugation and lyophilization. This study characterizes PLPC&rsq...

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Literature Corpus work
d4efcc04-f34d-5707-bc45-73469e803d16
DOI
10.20944/preprints202504.0471.v1
Open publication

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Beyond Exosomes: Ultrapurified Phospholipoproteic Complex (PLPC) as a Scalable Immunomodulatory Platform to Reprogram Immune Suppression in Metastatic CancerDOI 10.20944/preprints202504.0471.v1
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