Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systemically targeted cancer immunotherapy and gene delivery using transmorphic particles

27 Jun 2022

Abstract excerpt

Immunotherapy is a powerful tool for cancer treatment, but the pleiotropic nature of cytokines and immunological agents strongly limits clinical translation and safety. To address this unmet need, we designed and characterised a systemically targeted cytokine gene delivery system through transmorphic encapsidation of human recombinant adeno-associated virus DNA using coat proteins from a tumour-targeted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to RNA Interference and Gene Delivery
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35758207
DOI: 10.15252/emmm.202115418

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systemically targeted cancer immunotherapy and gene delivery using transmorphic particlesPMID 35758207Read ↗

Bacteriophages as Solid Tumor Theragnostic AgentsSemantic proximity Read ↗

Bacteriophages as Therapeutic and Diagnostic Vehicles in CancerSemantic proximity Read ↗

Programable Albumin-Hitchhiking Nanobodies Enhance the Delivery of STING Agonists to Potentiate Cancer ImmunotherapySemantic proximity Read ↗

Low-dose cytokine immunotherapy of solid cancers enabled by phagocytic-competent protein co-crystalsSemantic proximity Read ↗

iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapySemantic proximity Read ↗

Therapeutic immune cell engineering with an mRNA : AAV- <i>Sleeping Beauty</i> composite systemSemantic proximity Read ↗

Intratumoral delivered novel circular mRNA encoding cytokines for immune modulation and cancer therapySemantic proximity Read ↗

In vivo gene editing of T-cells in lymph nodes for enhanced cancer immunotherapySemantic proximity Read ↗

Sense-and-respond payload delivery using a novel antigen-inducible promoter improves suboptimal CAR-T activationSemantic proximity Read ↗

A novel immunogene therapy to cancer with high tumor selectivity and safetySemantic proximity Read ↗

T-cell specific in vivo gene delivery with DART-AAVs targeted to CD8Semantic proximity Read ↗

Optimizing Pancreatic Cancer Therapy: The Promise of Immune Stimulatory Oncolytic VirusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.