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Article

Molecular Engineering of Therapeutic Cytokines

2013-07-03

Abstract excerpt

Over the past three decades, a large body of work has been directed at the development of therapeutic cytokines. Despite their central role in immune modulation, only a handful of cytokine therapeutics has achieved regulatory approval. One of the major challenges associated with the therapeutic use of cytokines relates to their short serum half-life and low bioavailability. High doses are required to overcome thes...

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Identifiers and source

Literature Corpus work
cf4bce44-1217-5535-b8a6-09405e51afd9
DOI
10.3390/antib2030426
Open publication

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