Article

Psychotic-like experiences, polygenic risk scores for schizophrenia and structural properties of the salience, default mode and central-executive networks in healthy participants from UK Biobank

2019-08-09

Abstract excerpt

Schizophrenia is a highly heritable disorder with considerable phenotypic heterogeneity. Hallmark psychotic symptoms can be considered as existing on a continuum from non-clinical to clinical populations. Assessing genetic risk and psychotic-like experiences (PLEs) in non-clinical populations and their associated neurobiological underpinnings can offer valuable insights into symptom-associated brain mechanisms wit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c209ae86-e35b-588b-bfc0-06bff2ae80ff
DOI: 10.1101/729921

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Psychotic-like experiences, polygenic risk scores for schizophrenia and structural properties of the salience, default mode and central-executive networks in healthy participants from UK BiobankDOI 10.1101/729921Read

Pathway-based polygenic risk scores for schizophrenia and associations with clinical and neuroimaging phenotypes in UK BiobankSemantic proximity Read

Brain Heterogeneity in Schizophrenia and Its Association With Polygenic RiskSemantic proximity Read

Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort.Semantic proximity Read

Derivation and utility of schizophrenia polygenic risk associated multimodal MRI frontotemporal network.Semantic proximity Read

Refining Schizophrenia Risk Assessment: Machine Learning Delineates a Brain Signature of Cognitive Basic SymptomsSemantic proximity Read

Morphometric Analysis of Structural MRI Using Schizophrenia Meta-analytic Priors Distinguish Patients from Controls in Two Independent Samples and in a Sample of Individuals With High Polygenic Risk.Semantic proximity Read

Impact of schizophrenia-associated risk genes on brain functional networks and executive deficits: a study of individuals with schizophrenia and genetic high risk.Semantic proximity Read

The dark side of the mean: brain structural heterogeneity in schizophrenia and its polygenic riskSemantic proximity Read

Network localization of genetic risk for schizophrenia and bipolar disorder.Semantic proximity Read

What is the impact of genome-wide supported risk variants for schizophrenia and bipolar disorder on brain structure and function? A systematic review.Semantic proximity Read

Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia.Semantic proximity Read

The impact of genome-wide supported schizophrenia risk variants in the neurogranin gene on brain structure and function.Semantic proximity Read