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Article

Network localization of genetic risk for schizophrenia and bipolar disorder.

Psychological medicine - 3 Oct 2025

Yao Shanwen, Mo Fan, Rao Zhonghao, Shi Yu, Zhu Jiajia, Yu Yongqiang

Abstract excerpt

BACKGROUND: There is a considerable overlap in clinical features and genetics between schizophrenia (SZ) and bipolar disorder (BD). Previous neuroimaging research has demonstrated common and distinct brain damage patterns between relatives (RELs) of SZ and BD patients, suggesting shared and differential genetic influences on the brain. Despite an increasing recognition that disorders localize better to...

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PMID: 41039822
DOI: 10.1017/S0033291725101992
PMCID: PMC12527508

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