Article

Untargeted proteomics and stage-specific Huntington’s disease reveal biological pathways, and potential protein biomarkers

2024-06-18

Abstract excerpt

<title>Abstract</title> <p>Although Huntington’s Disease is a, monogenic neurodegenerative disease, its molecular manifestations remain highly complex and involve multiple cellular process. Here, we performed untargeted proteomics analysis of serum proteins in varying stages of HD severity. Our study identified pathways related to RHOGDI signaling, immune related pathways such as acute phase response signaling, c...

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Literature Corpus work: f98e02d2-103c-537d-be22-3f5a0892a110
DOI: 10.21203/rs.3.rs-4508811/v1

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