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Three-dimensional induced pluripotent stem-cell models of human brain angiogenesis

2020-02-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>During brain development, chemical cues released by developing neurons, cellular signaling with pericytes, and mechanical cues within the brain extracellular matrix (ECM) promote angiogenesis of brain microvascular endothelial cells (BMECs). Angiogenesis is also associated with diseases of the brain due to pathological chemical, cellular, and mechanical signalin...

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Literature Corpus work
c0e1a5d2-2f91-56f9-9ab9-71d9e0117320
DOI
10.21203/rs.2.23105/v1
Open publication

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Three-dimensional induced pluripotent stem-cell models of human brain angiogenesisDOI 10.21203/rs.2.23105/v1
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