Article

Three-dimensional induced pluripotent stem-cell models of human brain angiogenesis

2019-12-10

Abstract excerpt

<title>Abstract</title> <p>Background: During brain development, chemical cues released by developing neurons, cellular signaling with pericytes, and mechanical cues within the brain extracellular matrix (ECM) promotes angiogenesis occurs of brain microvascular endothelial cells (BMECs). During brain disease, angiogenesis can also occur due to pathological chemical, cellular, and mechanical signaling. Existing in...

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Literature Corpus work: 5d80135b-b7cd-5604-a6d0-702bd269c0d9
DOI: 10.21203/rs.2.18502/v1

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