Article

Nasal systems immunology identifies inflammatory and tolerogenic myeloid cells that determine allergic outcome following challenge

2020-09-10

Abstract excerpt

Innate mononuclear phagocytic system (MPS) cells preserve mucosal immune homeostasis. Here, we investigated their role at nasal mucosa following challenge with house dust mite. We combined single cell proteome and transcriptome profiling on immune cells from nasal biopsy cells of allergic rhinitis and non-allergic subjects, before and after repeated nasal allergen challenge. Nasal biopsies of patients showed infil...

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Literature Corpus work: c3a6de32-c0e0-5181-bdd7-deab9b5f452c
DOI: 10.1101/2020.09.09.20189886

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