Article

Atopic skin inflammation promotes systemic anaphylactic responses via IL-13 signaling in conventional dendritic cells.

2025-02-14

Abstract excerpt

<title>Abstract</title> <p>Cutaneous allergen sensitization (CAS) underlies atopic dermatitis (AD) and leads to various allergic symptoms, including food allergy and anaphylaxis. IL-13 expression by T follicular helper T (TFH) has been reported to be involved in generating high-affinity IgE antibodies and causing systemic anaphylaxis.1, 2 However, the mechanisms by which IL-13 triggers IgE-mediated allergic respo...

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Literature Corpus work: ed7d4f3c-f312-5575-8e68-db6faf37e567
DOI: 10.21203/rs.3.rs-5892170/v1

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