Detection and mutational consequences of embedded ribonucleotides

Abstract excerpt

Mutation is a fundamental driver of evolution. It occurs non-randomly throughout the genome, influenced by factors such as chromatin architecture, DNA replication, transcription and repair. In human populations an important, but poorly understood, subset of mutations are short insertions and deletions (indels), the formation of which has traditionally been ascribed to deficiencies in mismatch repair to correct pol...

Topics

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• DNA
• Genetic Variation
• Mutation
• Nanotechnology
• Nucleic Acid Hybridization
• Nucleotides
• Oligonucleotide Array Sequence Analysis
• Polymerase Chain Reaction

Identifiers and source

Literature Corpus work

c0b6fdca-3124-554a-91c4-0779b7cd19e3

DOI

10.7488/era/1116