Article
DNA Strand Displacement Reaction: A Powerful Tool for Discriminating Single Nucleotide Variants.
Topics in current chemistry (Cham) - 2 Jan 2020
Tang Weiyang, Zhong Weiye, Tan Yun, Wang Guan A, Li Feng, Liu Yizhen
Abstract excerpt
Single-nucleotide variants (SNVs) that are strongly associated with many genetic diseases and tumors are important both biologically and clinically. Detection of SNVs holds great potential for disease diagnosis and prognosis. Recent advances in DNA nanotechnology have offered numerous principles and strategies amenable to the detection and quantification of SNVs with high sensitivity, specificity, and...
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