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Label-Free Detection of DNA Mutations by Nanopore Analysis.

ACS applied materials & interfaces - 11 Apr 2018

Chen Xiaohan, M Roozbahani Golbarg, Ye Zijing, Zhang Youwen, Ma Rui, Xiang Jialing, Guan Xiyun

Abstract excerpt

Cancers are caused by mutations to genes that regulate cell normal functions. The capability to rapid and reliable detection of specific target gene variations can facilitate early disease detection and diagnosis and also enables personalized treatment of cancer. Most of the currently available methods for DNA mutation detection are time-consuming and/or require the use of labels or sophisticated instruments. In...

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PMID: 29537824
DOI: 10.1021/acsami.7b19774
PMCID: PMC6760912

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Source receipt: pubmed, retrieved 7 Sept 2026.

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