Article

Identification of Maternal-Effect Genes in Zebrafish using Maternal Crispants

2021-02-19

Abstract excerpt

In animals, early development is dependent on a pool of maternal factors, both RNA and proteins, which are required for basic cellular process and cell differentiation until zygotic genome activation. The role of a majority of these maternally expressed factors in adult fertility and early development is not fully understood. By exploiting the biallelic editing ability of CRISPR-Cas9 and the benefits of the zebraf...

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Literature Corpus work: c098fa4b-a194-50b0-8d99-fd19bb3dcdbb
DOI: 10.1101/2021.02.19.432057

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