Article
Maternal regulation of the vertebrate oocyte-to-embryo transition.
PLoS genetics - 1 Jul 2024
Fuentes Ricardo, Marlow Florence L, Abrams Elliott W, Zhang Hong, Kobayashi Manami, Gupta Tripti, Kapp Lee D, DiNardo Zachary, Heller Ronald, Cisternas Ruth, García-Castro Priscila, Segovia-Miranda Fabián, Montecinos-Franjola Felipe, Vought William, Vejnar Charles E, Giraldez Antonio J, Mullins Mary C
Abstract excerpt
Maternally-loaded factors in the egg accumulate during oogenesis and are essential for the acquisition of oocyte and egg developmental competence to ensure the production of viable embryos. However, their molecular nature and functional importance remain poorly understood. Here, we present a collection of 9 recessive maternal-effect mutants identified in a zebrafish forward genetic screen that reveal unique...
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