Maternal control of vertebrate development before the midblastula transition: mutants from the zebrafish I.

doi:10.1016/j.devcel.2004.05.002

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Article

Maternal control of vertebrate development before the midblastula transition: mutants from the zebrafish I.

Developmental cell - 1 Jun 2004

Dosch Roland, Wagner Daniel S, Mintzer Keith A, Runke Greg, Wiemelt Anthony P, Mullins Mary C

Abstract excerpt

Maternal factors control development prior to the activation of the embryonic genome. In vertebrates, little is known about the molecular mechanisms by which maternal factors regulate embryonic development. To understand the processes controlled by maternal factors and identify key genes involved, we embarked on a maternal-effect mutant screen in the zebrafish. We identified 68 maternal-effect mutants. Here we...

Topics

Animals
Blastula
Cell Division
Cell Polarity
Chromosome Mapping
Embryo, Nonmammalian
Female
Gene Expression Regulation, Developmental
Infertility, Male
Male
Mutation
Oocytes
Sex Differentiation
Sex Factors
Zebrafish

Source

Open in PubMed

Identifiers

PMID: 15177026
DOI: 10.1016/j.devcel.2004.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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