Article

A phenotypic brain organoid atlas for neurodevelopmental disorders

2025-09-13

Abstract excerpt

<h4>SUMMARY</h4> Thousands of genes are associated with neurodevelopmental disorders (NDDs), yet mechanisms and targeted treatments remain elusive. To fill these gaps, we present a CIRM-initiated NDD biobank of 352 publicly-available genetically-diverse patient-derived iPSCs, along with clinical details, brain imaging and genomic data, representing four major categories of disease: microcephaly (MIC), polymicrogy...

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Literature Corpus work: c058e8d4-c274-5d44-af20-4837df19e67e
DOI: 10.1101/2025.09.12.675864

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