Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systematic evaluation of B-cell clonal family inference approaches.

BMC immunology - 8 Feb 2024

Balashova Daria, van Schaik Barbera D C, Stratigopoulou Maria, Guikema Jeroen E J, Caniels Tom G, Claireaux Mathieu, van Gils Marit J, Musters Anne, Anang Dornatien C, de Vries Niek, Greiff Victor, van Kampen Antoine H C

Abstract excerpt

The reconstruction of clonal families (CFs) in B-cell receptor (BCR) repertoire analysis is a crucial step to understand the adaptive immune system and how it responds to antigens. The BCR repertoire of an individual is formed throughout life and is diverse due to several factors such as gene recombination and somatic hypermutation. The use of Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) using next...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Receptors, Antigen, B-Cell

Source

Open in PubMed Open full text

Identifiers

PMID: 38331731
DOI: 10.1186/s12865-024-00600-8
PMCID: PMC11370117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systematic evaluation of B-cell clonal family inference approaches.PMID 38331731Read ↗

Immunoglobulin heavy chains are sufficient to determine most B cell clonal relationships <sup>1</sup>Semantic proximity Read ↗

Evaluating methods for B-cell clonal family assignmentSemantic proximity Read ↗

Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing dataSemantic proximity Read ↗

Cutting Edge: Ig H Chains Are Sufficient to Determine Most B Cell Clonal RelationshipsSemantic proximity Read ↗

Exploring the impact of clonal definition on B-cell diversity: implications for the analysis of immune repertoiresSemantic proximity Read ↗

Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing data.Semantic proximity Read ↗

Fast Clonal Family Inference from Large-Scale B Cell Repertoire Sequencing DataSemantic proximity Read ↗

Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing DataSemantic proximity Read ↗

Combining mutation and recombination statistics to infer clonal families in antibody repertoires.Semantic proximity Read ↗

Practical guidelines for B-cell receptor repertoire sequencing analysisSemantic proximity Read ↗

Combining mutation and recombination statistics to infer clonal families in antibody repertoiresSemantic proximity Read ↗

Quantifying B-cell Clonal Diversity In Repertoire DataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.