Article

DNA Repair Gene Expression Adjusted by the PCNA Metagene Predicts Survival in Multiple Cancers

2019-02-04

Abstract excerpt

Removal of the proliferation component of gene expression by PCNA adjustment has been addressed in numerous survival prediction studies for breast cancer and all cancers in the TCGA. These studies indicate that widespread co-regulation of proliferation upwardly biases survival prediction when gene selection is performed on a genome-wide basis. In addition, removal of the correlative effects of proliferation does n...

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Literature Corpus work: c052009f-79c7-5c2c-b43f-b6cd8f005c1c
DOI: 10.20944/preprints201902.0042.v1

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