Article

Classifying cancer genome aberrations by their mutually exclusive effects on transcription

2017-03-31

Abstract excerpt

<h4>Background</h4> Malignant tumors are typically caused by a conglomeration of genomic aberrations—including point mutations, small insertions, small deletions, and large copy-number variations. In some cases, specific chemotherapies and targeted drug treatments are effective against tumors that harbor certain genomic aberrations. However, predictive aberrations (biomarkers) have not been identified for many tu...

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Literature Corpus work: 033eab49-1b4f-5c1f-a7d7-3995e9e21d89
DOI: 10.1101/122549

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