Article
Genome-wide identification and analysis of prognostic features in human cancers.
Cell reports - 29 Mar 2022
Smith Joan C, Sheltzer Jason M
Abstract excerpt
Clinical decisions in cancer rely on precisely assessing patient risk. To improve our ability to identify the most aggressive malignancies, we constructed genome-wide survival models using gene expression, copy number, methylation, and mutation data from 10,884 patients. We identified more than 100,000 significant prognostic biomarkers and demonstrate that these genomic features can predict patient outcomes in...
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