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Integration of multi-omics data shows downregulation of mismatch repair, purin, and tubulin pathways in triple-negative chemotherapy-resistant breast tumors

2022-08-17

Abstract excerpt

<h4>Background: </h4> Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Patients with TNBC are primarily treated with neoadjuvant chemotherapy (NAC). Response to NAC is prognostic, with reductions in low overall survival and disease-free survival rates in those patients who do not achieve pathological complete response (pCR). Based on this premise, we focused on patients with resid...

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Literature Corpus work
375d9ff7-108f-524d-a23a-74363470fc0a
DOI
10.21203/rs.3.rs-1954567/v1
Open publication

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