Article

Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability

2024-11-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Limited understanding of the biology predisposing certain human papillomavirus-related (HPV+) oropharyngeal squamous cell carcinomas (OPSCCs) to relapse impedes therapeutic personalization. We aimed to identify molecular traits that distinguish recurrence-prone tumors. <h4>Methods</h4> 50 HPV+ OPSCCs that later recurred (cases) and 50 non-recurrent controls matched for stag...

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Literature Corpus work: 5cba04bd-8dcc-5784-a8ae-f1d768b514ed
DOI: 10.1101/2024.10.31.621311

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