Article

Pan-cancer analysis of non-oncogene addiction to DNA repair

2021-09-03

Abstract excerpt

<title>Abstract</title> <p>Cancer cells usually depend on the aberrant function of one or few driver genes to initiate and promote their malignancy, an attribute known as oncogene addiction. However, cancer cells might become dependent on the normal cellular functions of certain genes that are not oncogenes but ensure cell survival (non-oncogene addiction). The downregulation of DNA repair genes and the consequen...

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Literature Corpus work: e35cf4ae-5d53-5538-91c1-842fdc008c4a
DOI: 10.21203/rs.3.rs-846744/v1

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