Article

An integrated analysis of the epigenetic, genetic, and transcriptional patterns associated with outcome across cancer types

2017-09-08

Abstract excerpt

Successful treatment decisions in cancer depend on the accurate assessment of patient risk. To improve our understanding of the molecular alterations that underlie deadly malignancies, we analyzed genomic profiles from 33,036 solid tumors with known patient outcomes. Contrary to expectations, we find that mutations in cancer driver genes are almost never associated with patient survival time. In contrast, copy num...

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Literature Corpus work: 23ef2412-ea7d-5de3-b8ad-52b6be40a79b
DOI: 10.1101/186528

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