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Article

The TNF <sup>ΔARE</sup> mouse as a model of intestinal fibrosis

2023-01-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> Crohn’s disease (CD) is a highly morbid chronic inflammatory disease. The majority of CD patients also develop fibrostenosing complications. Despite this, there are no medical therapies for intestinal fibrosis. This is in part due to lack of high-fidelity biomimetic models to enhance understanding and drug development. There is a need to develop in vivo models of inf...

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Literature Corpus work
c03edba9-67cc-5581-9440-71221d814efc
DOI
10.1101/2023.01.13.523973
Open publication

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The TNF <sup>ΔARE</sup> mouse as a model of intestinal fibrosisDOI 10.1101/2023.01.13.523973
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