Article

Pericyte-tumor crosstalk facilitates metastatic tumor cell latency through PIEZO1-activated lysophospholipid transfer

2025-02-17

Abstract excerpt

Tumor dissemination is increasingly recognized to begin early in tumor development. Although most of these early disseminated cells are cleared, some survive and persist below clinical detection, acting as reservoirs for metastatic relapse. Metastatic tumor cells often rely on interactions with local stromal cells to support their colonization. In this study, we propose that pericyte-tumor cell interactions promot...

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Identifiers and source

Literature Corpus work: c029343f-e178-5b6a-8f62-135c529338e8
DOI: 10.1101/2025.02.15.638347

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