Article
Mapping EGFR1 sorting domains in endosomes with a calibrated 3D expansion microscopy toolkit
2025-10-02
Abstract excerpt
Endosomes are nanoscale intracellular compartments that sort and recycle cell surface receptors such as epidermal growth factor receptor 1 (EGFR1). Nanometre-scale interactions and co-clustering of signalling proteins, cargo, and the membrane are critical to this process. Direct visualisation of these interactions has been hindered by the limited 3D resolution achievable with conventional and super-resolution micr...
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Identifiers and source
- Literature Corpus work
- bfc60847-f241-5241-900e-7de6d0bd1263
- DOI
- 10.1101/2025.10.01.678490