Article

Quantitative profiling of lysosomal accumulation through label-free biomarkers via High-Content Holo-Tomographic Flow Cytometry

2025-03-13

Abstract excerpt

Lysosomal storage diseases (LSDs) are genetic disorders caused by enzyme deficiencies that lead to lysosomal dysfunction and progressive cell damage. Accurate visualization and quantification of lysosomes are essential for understanding disease progression and developing effective therapies. Here, for the first time, we successfully identified and characterized lysosomes using an innovative Holo-Tomographic Flow C...

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Literature Corpus work: d7db0377-173c-5723-b823-9bd9c5c27675
DOI: 10.1101/2025.03.11.642563

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