Rab27-dependent egress of SARS-CoV-2 via secretory amphisomes

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, hijacks host cellular machinery to replicate and spread. Understanding how SARS-CoV-2 reorganizes host cell architecture to accommodate this is essential for elucidating its pathogenesis and identifying therapeutic targets. While the molecular mechanisms of SARS-CoV-2 entry are well characterized, the pathways governing...

Topics

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• Autophagy in Disease and Therapy
• Calcium signaling and nucleotide metabolism
• Influenza Virus Research Studies
• interferon and immune responses
• Lipid Membrane Structure and Behavior
• Mosquito-borne diseases and control
• SARS-CoV-2 and COVID-19 Research
• Viral Infections and Outbreaks Research

Identifiers and source

Literature Corpus work

d188419f-3456-5cf2-a805-df1cb1082011

DOI

10.64898/2025.12.15.694351