Article

Live-cell Fluorescence Microscopy of HSV-1 Cellular Egress by Exocytosis

2023-02-28

Abstract excerpt

1.1 The human pathogen Herpes Simplex Virus 1 (HSV-1) produces a lifelong infection in the majority of the world’s population. While the generalities of alpha herpesvirus assembly and egress pathways are known, the precise molecular and spatiotemporal details remain unclear. In order to study this aspect of HSV-1 infection, we engineered a recombinant HSV-1 strain expressing a pH-sensitive reporter, gM-pHluorin. U...

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Literature Corpus work: 231809ac-caca-597c-98cc-b9277f1436ff
DOI: 10.1101/2023.02.27.530373

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