Article

HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging

2023-02-07

Abstract excerpt

Expansion microscopy (ExM) enables nanoscale imaging using a standard confocal microscope through the physical, isotropic expansion of fixed immunolabeled specimens. ExM is widely employed to image proteins, nucleic acids, and lipid membranes in single cells; however, current methods limit the number of samples that can be processed simultaneously. We developed High-throughput Expansion Microscopy (HiExM), a robus...

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Literature Corpus work: a691b7a0-80a0-5d2b-bdad-1b22d3c19c43
DOI: 10.1101/2023.02.07.527509

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