Article

Nanoscale Imaging of Biomolecules using Molecule Anchorable Gel-enabled Nanoscale In-situ Fluorescence Microscopy

2021-09-03

Abstract excerpt

<title>Abstract</title> <p>Expansion microscopy (ExM) is a powerful imaging strategy that offers a low-cost solution for nanoimaging with conventional microscopes by physically and isotropically magnifying preserved biological specimens embedded in a cross-linked water-swellable hydrogel. Current ExM protocols require prior treatment with specialized reactive anchoring chemicals to link specific labels and biomol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 826d144b-8172-52bb-b462-7f7ddf281754
DOI: 10.21203/rs.3.rs-858006/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Nanoscale Imaging of Biomolecules using Molecule Anchorable Gel-enabled Nanoscale In-situ Fluorescence MicroscopyDOI 10.21203/rs.3.rs-858006/v1Read

Hydrogel Fiber EndomicroscopySemantic proximity Read

Decrowding Expansion Pathology: Unmasking Previously Invisible Nanostructures and Cells in Intact Human Brain Pathology SpecimensSemantic proximity Read

Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosuresSemantic proximity Read

HiExM: high-throughput expansion microscopy enables scalable super-resolution imagingSemantic proximity Read

Active microrheology using pulsed optical tweezers to probe viscoelasticity of Lamin A towards diagnosis of laminopathiesSemantic proximity Read

Mapping EGFR1 sorting domains in endosomes with a calibrated 3D expansion microscopy toolkitSemantic proximity Read

Cellular and Molecular Probing of Intact Transparent Human OrgansSemantic proximity Read

Structural and molecular interrogation of intact biological systems.Semantic proximity Read

Label-free nanoscale mapping of intracellular organelle chemistrySemantic proximity Read

MicroMagnify: a multiplexed expansion microscopy method for pathogens and infected tissuesSemantic proximity Read

Super-resolved polarisation-enhanced second harmonic generation for direct imaging of nanoscale changes in collagen architectureSemantic proximity Read

ADAPT-3D: Accelerated Deep Adaptable Processing of Tissue for 3-Dimensional Fluorescence Tissue Imaging for Research and Clinical SettingsSemantic proximity Read